Random Rants

[Black Orchid]

That's what you call a Barbour. Actually gets my respect for that…

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[Chris]

@Megatron1505:

Barbour is for royalty and farmers 

Well, the family history definitely qualifies me for purchase as one of the latter.

[Megatron1505]

Is this a Barbour?

[Black Orchid]

Noooooooo

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[Megatron1505]

This week I was off work with tonsillitis, went to see my doctor who gave me an anti biotic to clear it up. Due to my fucked up immune system I also get allergy type reactions when my immune system is low (swellings and stuff, basically my body massively overreacts to infections), went back to the doctor and he gave me steroids to clear that up.

My curious nature forced me to google the medications to check if they reacted with each other and I was shocked to find that combined they have a life threatening reaction, the anti biotic dramatically strengthens the steroid which leads to over dose.

So I can take one or the other, do I keep the tonsillitis or the allergy type reaction….decision, decisions....

Conclusion. My doctor is a fucking idiot.

Serious - Use Alternative
Possible serious or life-threatening interaction. Monitor closely. Use alternatives if available.
clarithromycin oral and prednisone oral

clarithromycin oral will increase the level or effect of prednisone oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism.

http://www.rxlist.com/drug-interactions/clarithromycin-oral-and-prednisone-oral-interaction.htm

[steelworker]

@Megatron1505:

This week I was off work with tonsillitis, went to see my doctor who gave me an anti biotic to clear it up. Due to my fucked up immune system I also get allergy type reactions when my immune system is low (swellings and stuff, basically my body massively overreacts to infections), went back to the doctor and he gave me steroids to clear that up.

My curious nature forced me to google the medications to check if they reacted with each other and I was shocked to find that combined they have a life threatening reaction, the anti biotic dramatically strengthens the steroid which leads to over dose.

So I can take one or the other, do I keep the tonsillitis or the allergy type reaction….decision, decisions....

Conclusion. My doctor is a fucking idiot.

Serious - Use Alternative
Possible serious or life-threatening interaction. Monitor closely. Use alternatives if available.
clarithromycin oral and prednisone oral

clarithromycin oral will increase the level or effect of prednisone oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism.

http://www.rxlist.com/drug-interactions/clarithromycin-oral-and-prednisone-oral-interaction.htm

Wtf! time to see a new M.D.

[Seth]

@mega. It might be worth asking if there is an anti-biotic and steroid combination that does not have the interaction you describe. There are so many anti-biotic options available, I suspect they can adjust one to work with the other.

p.s. happened to a relative of mine too. Had a multi-prescription interaction that sent them to the ER. I don't understand why there are not automatic flags in a database that indicate the interaction issues with multi-prescriptions.

[Snowy]

Any chance your Dr factored that into what he gave you?

[louisbosco]

maybe he didnt know/remembered you were on antibiotics and gave you the steriods… usually if i've to go back to a doctor, i'll let them know what meds i'm still on so that they wouldn't give one that would have any adverse reaction while taking the other.

[Giles]

@Snowy:

Any chance your Dr factored that into what he gave you?

Any chance your Dr is getting bored of seeing you?

[Megatron1505]

@Giles:

@Snowy:

Any chance your Dr factored that into what he gave you?

Any chance your Dr is getting bored of seeing you?

Probably this, the visits were 2 days apart.

[Snowy]

One of my neighbors has a battery dying in a smoke detector. I've been hearing it 'beep' every minute for 3 days now. Fuck me, how hard is it to replace a battery! (or maybe they're dead, and fuck me can't someone stop that beeping, they're dead!)

[Black Orchid]

Phone the fire brigade that will sort the neighbours out! [emoji35] your social duty of course…

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[Snowy]

Good idea BlackO. If it keeps up and I get much more twitchy (incase you can't tell), I'll be giving them a very friendly tip

[jdl1279]

21" of fresh snow overnight. Everything is closed today including all Federal and State government posts…but this asshole still has to work tonight. Would it be too much to ask for some IHxWesco snowshoes?

[mclaincausey]

I'm glad overprotective dipshit parents are allowing their idiotic superstitions to put entire populations at risk from diseases we shouldn't have to worry about anymore. The whole lot should be sterilized.

[trail and arrow]

??? ???

[Qinhan]

@mclaincausey:

I'm glad overprotective dipshit parents are allowing their idiotic superstitions to put entire populations at risk from diseases we shouldn't have to worry about anymore. The whole lot should be sterilized.

This!  ^

Edit: although sterilisation might be taking it a little too far.

[Omega Man]

It's going to be a cold night in Toronto.  Temp -23C, -34C with wind-chill  >:(.

[Finn666]

if you're concerned that you have a heart attack or such thing…don't call the ambulance

930USD!... what the fuck!?