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    Iron Heart Fall/Winter 2025 Collection Preview - Now Live

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    • hecticH
      hectic
      Joined:

      Melatonin is a pineal hormone that plays a central part in regulating bodily rhythms and has been used as a drug to re-align them with the outside world…

      ...Nine of the ten trials found that melatonin, taken close to the target bedtime at the destination (10pm to midnight), decreased jet-lag from flights crossing five or more time zones. Daily doses of melatonin between 0.5 and 5mg are similarly effective, except that people fall asleep faster and sleep better after 5mg than 0.5mg. Doses above 5mg appear to be no more effective. The relative ineffectiveness of 2mg slow-release melatonin suggests that a short-lived higher peak concentration of melatonin works better. Based on the review, the number needed to treat (NNT) is 2. The benefit is likely to be greater the more time zones are crossed, and less for westward flights. The timing of the melatonin dose is important: if it is taken at the wrong time, early in the day, it is liable to cause sleepiness and delay adaptation to local time. The incidence of other side effects is low. Case reports suggest that people with epilepsy, and patients taking warfarin may come to harm from melatonin.

      Random fact: I took part in medical trials for melatonin usage in the 90's, I had to sit in front of giant light lamps and disrupt my sleep cycle; paid quite well.

      last edited by 1 Reply Last reply Reply Quote 0
      • SeulS
        Seul
        Joined:

        These days only my job disrupts my sleep cycle - and it doesn't pay well.

        last edited by 1 Reply Last reply Reply Quote 0
        • GilesG
          Giles
          IHUK Crew
          Joined:

          @hectic:

          paid quite well.

          But look what it did to your body….. 😉 😉 😉 😉

          "OK face up to it - you're useless but generally pretty honest and straightforward . . . it's a rare combination of qualities that I have come to admire in you" - Geo 2011

          last edited by 1 Reply Last reply Reply Quote 0
          • DougNgD
            DougNg
            Joined:

            They're over the counter dietary supplements. You're able to get them in any grocery/health food store here, but you guys tend to be in a nanny state when it comes to over the counter drugs, so I'm not sure

            I know violence is not the answer, I got it wrong on purpose

            last edited by 1 Reply Last reply Reply Quote 0
            • hecticH
              hectic
              Joined:

              @ Giles - no damn supper powers though.

              @ Doug - yeah, pussy nation here, I'm pretty sure we cant buy them

              last edited by 1 Reply Last reply Reply Quote 0
              • DougNgD
                DougNg
                Joined:

                Public service announcement: all you folks in the Mid Atlantic on up, get ready for Hurricane Sandy. She's about to kick our asses

                Gas generator with gas: check
                Propane tank full: check
                Water and shelf stable food: check
                Cars gassed up: check

                I know violence is not the answer, I got it wrong on purpose

                last edited by 1 Reply Last reply Reply Quote 0
                • bagley920B
                  bagley920
                  Joined:

                  Where you at Doug? I haven't looked. What's the projected landfall. Last I saw she was gonna go away from the coast

                  If I am not I, who will be? -Henry David Thoreau

                  last edited by 1 Reply Last reply Reply Quote 0
                  • DougNgD
                    DougNg
                    Joined:

                    Maryland. About twenty miles west of Annapolis

                    Last I heard, it's going to hit us right on the nose

                    I know violence is not the answer, I got it wrong on purpose

                    last edited by 1 Reply Last reply Reply Quote 0
                    • Megatron1505M
                      Megatron1505
                      見習いボス
                      Joined:

                      Stay safe Ng's.

                      Made in England, clothed in Japan, fed in America and drunk in Belgium !

                      last edited by 1 Reply Last reply Reply Quote 0
                      • Finn666F
                        Finn666
                        Joined:

                        stay safe mate (and all others in the same region!)…

                        last edited by 1 Reply Last reply Reply Quote 0
                        • ChrisC
                          Chris
                          Raw and Unwashed
                          Joined:

                          Yeah, stay safe, Doug.  Good to see you're properly prepped.  Hurricanes suck.  A lot.

                          last edited by 1 Reply Last reply Reply Quote 0
                          • DougNgD
                            DougNg
                            Joined:

                            Shotgun: check
                            Knives: check
                            Bow and arrow: check

                            Just in case the storm comes with a side of zombies

                            I know violence is not the answer, I got it wrong on purpose

                            last edited by 1 Reply Last reply Reply Quote 0
                            • thomasnunnallyT
                              thomasnunnally
                              Joined:

                              Yea Doug, sounds like you are preparing for the apocalypse, not a hurricane!

                              Out with the new! In with the old!

                              last edited by 1 Reply Last reply Reply Quote 0
                              • J-IVJ
                                J-IV
                                啓蒙家
                                Joined:

                                Too much Walking Dead

                                I'm as ugly as you

                                last edited by 1 Reply Last reply Reply Quote 0
                                • SeulS
                                  Seul
                                  Joined:

                                  @DougNg:

                                  Shotgun: check
                                  Knives: check
                                  Bow and arrow: check

                                  Just in case the storm comes with a side of zombies

                                  Brilliant. But seriously: be safe mate!..

                                  last edited by 1 Reply Last reply Reply Quote 0
                                  • injunjackI
                                    injunjack
                                    見習いボス
                                    Joined:

                                    Doug

                                    You need a hatchet, machete, and aluminum baseball bat and probably good old katana wouldn't do any harm, in case you run out of ammo, and that hurricane comes with Walkers….

                                    last edited by 1 Reply Last reply Reply Quote 0
                                    • SeulS
                                      Seul
                                      Joined:

                                      Weird coincidence at work… Came up with 68 ordered items whilst wearing my... Yep: IHSH-68...

                                      last edited by 1 Reply Last reply Reply Quote 0
                                      • JiiJ
                                        Jii
                                        Joined:

                                        Walking to work this morning:

                                        That's right, it's snowing. In october. If it wasn't in Finland I'd post in random rants 🙂

                                        AIAN HA-TO!

                                        last edited by 1 Reply Last reply Reply Quote 0
                                        • injunjackI
                                          injunjack
                                          見習いボス
                                          Joined:

                                          Jii

                                          You can put it well on rants….and again suckers couldn't drive carefully, quite many crashes this morning.

                                          last edited by 1 Reply Last reply Reply Quote 0
                                          • hecticH
                                            hectic
                                            Joined:

                                            This is mellow: www.globegenie.com

                                            last edited by 1 Reply Last reply Reply Quote 0
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